Difference between revisions of "User:Z3324681"

From CellBiology
(Individual Assessments)
(Individual Assessments)
Line 16: Line 16:
 
Copyright: © 2011 Pilhofer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 
Copyright: © 2011 Pilhofer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
  
 +
--[[User:Z8600021|Mark Hill]] ([[User talk:Z8600021|talk]]) 11:06, 11 April 2013 (EST) This image is uploaded correctly with all required associated information.
 
===Lab 2===
 
===Lab 2===
 
'''Identify a recent research article (not review) that uses either confocal microscopy or super-resolution microscopy as one of the study's techniques. Explain briefly (1 paragraph) how the microscopy technique specifically contributed to the article's findings.'''
 
'''Identify a recent research article (not review) that uses either confocal microscopy or super-resolution microscopy as one of the study's techniques. Explain briefly (1 paragraph) how the microscopy technique specifically contributed to the article's findings.'''
Line 21: Line 22:
  
 
This study examined the chemotherapeutic drug doxorubicin (DOX) with the novel sixth-generation cationic poly-l-lysine dendrimer (DM) and determined enhanced therapeutic efficacy of DOX when complexed to DM in tumour-bearing mice. Confocal microscopy allowed evaluation of the depth of distribution of both drugs (DOX and DOX-DM) into the Multicellular Tumour Spheroids (MTS)bu the following method. For each image, intensity from background fluorescence was obtained from untreated MTS and subtracted from total intensity. The total fluoresence intensity was then calculated in each region of interest and plotted as a function of the distance from the spheroid rim.  <ref><pubmed>23527750</pubmed></ref>
 
This study examined the chemotherapeutic drug doxorubicin (DOX) with the novel sixth-generation cationic poly-l-lysine dendrimer (DM) and determined enhanced therapeutic efficacy of DOX when complexed to DM in tumour-bearing mice. Confocal microscopy allowed evaluation of the depth of distribution of both drugs (DOX and DOX-DM) into the Multicellular Tumour Spheroids (MTS)bu the following method. For each image, intensity from background fluorescence was obtained from untreated MTS and subtracted from total intensity. The total fluoresence intensity was then calculated in each region of interest and plotted as a function of the distance from the spheroid rim.  <ref><pubmed>23527750</pubmed></ref>
 +
  
 
===Lab 3===
 
===Lab 3===

Revision as of 12:06, 11 April 2013

Lab Attendance

--Z3324681 (talk) 15:54, 14 March 2013 (EST)

--Z3324681 (talk) 15:50, 21 March 2013 (EST)

--Z3324681 (talk) 15:10, 28 March 2013 (EST)

Individual Assessments

Lab 1

Bacterial and Eukaryotic Microtubule Structure.png

Structural Model of Bacterial and Eukaryotic Microtubules [1]

Reference: Pilhofer M, Ladinsky MS, McDowall AW, Petroni G, Jensen GJ (2011) Microtubules in Bacteria: Ancient Tubulins Build a Five-Protofilament Homolog of the Eukaryotic Cytoskeleton. PLoS Biol 9(12): e1001213. doi:10.1371/journal.pbio.1001213

Copyright: © 2011 Pilhofer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

--Mark Hill (talk) 11:06, 11 April 2013 (EST) This image is uploaded correctly with all required associated information.

Lab 2

Identify a recent research article (not review) that uses either confocal microscopy or super-resolution microscopy as one of the study's techniques. Explain briefly (1 paragraph) how the microscopy technique specifically contributed to the article's findings.


This study examined the chemotherapeutic drug doxorubicin (DOX) with the novel sixth-generation cationic poly-l-lysine dendrimer (DM) and determined enhanced therapeutic efficacy of DOX when complexed to DM in tumour-bearing mice. Confocal microscopy allowed evaluation of the depth of distribution of both drugs (DOX and DOX-DM) into the Multicellular Tumour Spheroids (MTS)bu the following method. For each image, intensity from background fluorescence was obtained from untreated MTS and subtracted from total intensity. The total fluoresence intensity was then calculated in each region of interest and plotted as a function of the distance from the spheroid rim. [2]


Lab 3

1. Select 4 reference papers related to your selected topic sub-section. Read these papers and write a brief description of their findings and relevance to the selected topic sub-section. The reference along with your description should then be pasted on both your group discussion page and your own personal page. 2. Select an image related to your selected topic sub-section (this can be from one of the 4 above or from elsewhere). The image should be uploaded (with all the required information: description, reference, copyright and student template) and pasted onto the project page sub-section and onto your own personal page.

References

  1. <pubmed>22162949</pubmed>
  2. <pubmed>23527750</pubmed>


Formatting Experiments

Linking things within the page and renaming said links: Lecture 1 is the same link as Cell_Biology_Introduction

Linking things outside the page and renaming said links: Google it! is the same link as [1]

Pictures: Resizing and repositioning

Red White Blood cells 01.jpg

Pictures: Thumbnail and Renaming

OMGCELLS

Dot points:

  • wow
  • bang
  • pop

Referencing: 1. find the number, remove colon.

PMID 23393914


2. Put pubmed code at front and end.

(pubmed)23393914(/pubmed)


3. Put ref code at front and end

(ref)(pubmed)23393914(/pubmed)(/ref)