Talk:2015 Group 6 Project
Group Assessment Criteria
- The key points relating to the topic that your group allocated are clearly described.
- The choice of content, headings and sub-headings, diagrams, tables, graphs show a good understanding of the topic area.
- Content is correctly cited and referenced.
- The wiki has an element of teaching at a peer level using the student's own innovative diagrams, tables or figures and/or using interesting examples or explanations.
- Evidence of significant research relating to basic and applied sciences that goes beyond the formal teaching activities.
- Relates the topic and content of the Wiki entry to learning aims of cell biology.
- Clearly reflects on editing/feedback from group peers and articulates how the Wiki could be improved (or not) based on peer comments/feedback. Demonstrates an ability to review own work when criticised in an open edited wiki format. Reflects on what was learned from the process of editing a peer's wiki.
- Evaluates own performance and that of group peers to give a rounded summary of this wiki process in terms of group effort and achievement.
- The content of the wiki should demonstrate to the reader that your group has researched adequately on this topic and covered the key areas necessary to inform your peers in their learning.
- Develops and edits the wiki entries in accordance with the above guidelines.
Hey, so I've just been looking around for a topic and maybe we could do something related to the fibres that make up the extracellular matrix e.g. collagen or elastin? I'm not sure though, what do you guys suggest? --Z5016650 (talk) 21:56, 22 March 2015 (EST)
- Collagen - has the most information, if we want to do this topic we have to lock it in ASAP.
- Hydrated Matrix
- Support for cells
- Pattern of ECM regulates:
- cell division
- growth factors
I think it is most likely that the topic will be broken up into structures but we may also be able to talk about the origin of EM and the function (although this may be a component of each structure that we have to discuss).
Z3333429 (talk) 00:47, 24 March 2015 (EST) I haven't heard back from Dr Hill yet. I won't be at the lecture tomorrow because I have a physio appointment so maybe ask him in the first 5 mins of the lecture just to make sure we have locked out topic in.
--Z5050795 (talk) 17:28, 26 March 2015 (EST) Hi, guys! I`m late too.. Sorry about that. The topic sounds good! My name is Laura, I`m brazilian. I`m kind of lost in everything but i really want to work and contribute with the project. I just need to understand what is going on.. Please, don`t hesitate on saying to me what you think i should listen.. =)
Collagen Type II: Function
This article suggests that the extracellular matrix of the cartilage is mainly composed of type II collagen. In healthy cartilage, type II collagen is not degraded. However, when it is degraded by enzymes this causes joint damage, this is what occurs in osteoarthritis.
In this article, it says collagen type II along with other proteins, has a role in skeletal development. Collagen II also interacts with minor collagens IX and XI to form heterotypic fibrils. Mutations in type II collagen in the extracellular matrix of the vertebrae show the important structural and developmental role of the fibrillar network.
In this article, it mentions that type II collagen is found in articular cartilage, which acts as a load bearing, low-friction, wear-resistant cushion. It is located at the ends of long bones to allow skeletal movement that is painless.
This article says that type II collagen plays an essential role in both fracture healing and long bone development. It is also mentioned that an increased production of type II collagen could enhance full bone formation. Type II collagen promotes bone marrow derived mesenchymal stem cell (BMSC) osteogenesis and inhibits adipogenesis. This means that collagen II may have a function in the early stage of BMSC differentiation.