Talk:2011 Group 4 Project

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Revision as of 10:43, 31 March 2011 by S8600021 (talk | contribs)

Post Peer Assessment Discussion

Hey guys in response to the peers i moved around my pictures, gave them text under them, and added a lot of new information and some photos to the structure section. the only issue we have left is to clean up our reference list since it mostly looks like a bunch of pubmed IDs. i guess we will ask mark what to do with this.--Michael Orenstein 21:48, 25 May 2011 (EST)

Week 7

  • This is the week before the mid-session break.
  • In the lab this week we will have an opportunity to discuss any issues which are slowing progress on your project.
  • The Thursday of the week beginning 02 May will be when all projects will be open to Peer Assessment.
  • What you have on your page by Thursday of that week will be the content that others in the class will comment upon.

Week 6

  1. I see many groups now have subsection titles for their projects.
  2. Here are some searches: Pubmed search all databases junction | PLoS junction | JCB junction You can now simply put your own search term into each top window.
  3. Now's the time to get your images, movies, media etc uploaded. Biomed central | JCB | JCB Archive | PLoS. Once uploaded you can make a gallery on either your project or discussion page using <gallery>File:name here</gallery> tags with your image files listed between the tags. When you upload project images, add this text as it appears replacing # with your own Group number to the summary information [[Category:2011Project#]].
  4. Shown below are the criteria that will be used to assess your final project.

Group Assessment Criteria

  • The key points relating to the topic that your group was allocated are clearly described.
  • The choice of content, headings and sub-headings, diagrams, tables, graphs show a good understanding of the topic area.
  • Content is correctly cited and referenced.
  • The wiki has an element of teaching at a peer level using the student’s own innovative diagrams, tables or figures and/or using interesting examples or explanations.
  • Evidence of significant research relating to basic and applied sciences that goes beyond the formal teaching activities.
  • Relates the topics and content of the Wiki entry to learning aims of cell biology.
  • Clearly reflects on editing/feedback from group peers and articulates how the Wiki could be improved (or not) based on peer comments/feedback. Demonstrates an ability to review own work when criticised in an open edited wiki format. Reflects on what was learned from the process of editing a peer’s wiki.
  • Evaluates own performance and that of group peers to give a rounded summary of this wiki process in terms of group effort and achievement.
  • The content of the wiki should demonstrate to the reader that your group has researched adequately on this topic and covered the key areas necessary to inform your peers in their learning.
  • Develops and edits the wiki entries in accordance with this sites wiki guidelines.


By Week 5

Each Group member has added to the discussion page:

  1. A Review Article
  2. A Historic Research Article
  3. A Current Research Article

No two students should add the same paper and there should be a link to the original article.

--Mark Hill 17:14, 30 March 2011 (EST) OK Group 4, Just one student (Z3288729) trying to organise an online discussion to date and no content added by any other group member to either your discussion or project page. Also no response to Z3288729 request about the project topic. You were meant to have already begun looking into both the topic and references, pasting links on your discussion page. I will see you in the lab tomorrow to discuss whether you are having problems or are simply not doing the work. This search should get you started. Search Pubmed: Desmosome

Discussions

Firstly, is everybody happy with the topic that was decided upon last week? Next, we need to divide ourselves into sections of the topic. What if we divided it into:


Structure and function

Related abnormalities

Current research methods

Current and future possibilities for research


I personally would be most interested in researching the related abnormalities.\

(z3288729) S.J

(z3217345) M.B (Preference for structure and function)

(z3289066) E.K current research methods is good

I think that we need to go into a lot more detail with the layout and division of work between us. If anyone could help with this it would be much appreciated. We could possibly look into how they were first discovered also? I had a quick look at function, and there is HEAPS. This should become a separate subject area. With structure, we could look into location within the cell as well? Hemidesmosomes needs to be addressed, not in a huge amount of detail but it cannot be ignored. --Sarah Jenkins 11:01, 30 March 2011 (EST)


Since there won't be much information about current research methods, I'm happy to do hemidesmosomes as well.--Elisabeth Karsten 11:04, 30 March 2011 (EST)

Great. I was thinking that we shouldn't have way too much on related abnormalities, so I can work on the structure as well?? And then leave function to Z3217345 --Sarah Jenkins 11:07, 30 March 2011 (EST)


Ideas

I am happy to take on the role of team manager if everyone thinks im up to it? I agree that we do need some authority and I like the idea of all of us working on each section before moving on to the next one. --Sarah Jenkins 08:52, 31 March 2011 (EST)

Research Areas

Structure and function

z3217345

General desmosome information: http://www.ncbi.nlm.nih.gov/pubmed/20066089

Desmosome assembly and cell-cell adhesion are membrane raft-dependent processes: http://www.ncbi.nlm.nih.gov/pubmed/21071449

Cellular and molecular biology of the desmosome: - Mechanical continuity is provided by desmosomes and adherens junctions http://www.ncbi.nlm.nih.gov/pubmed/20847325

The desmosome in the epidermis and myocardium: http://www.ncbi.nlm.nih.gov/pubmed/18957846

Desmosome structure, composition and function: http://www.ncbi.nlm.nih.gov/pubmed/17854763

Milestones in Investigative Dermatology: The Desmosome: http://www.ncbi.nlm.nih.gov/pubmed/21270799

Biochemical Characterization of the Desmosome: http://www.ncbi.nlm.nih.gov/pubmed/21270806

Regulation of desmosome assembly and adhesion: http://www.ncbi.nlm.nih.gov/pubmed/15561586

Mechanisms of desmosome assembly and disassembly: http://www.ncbi.nlm.nih.gov/pubmed/12472547

The desmosome: structure, function and acquired pathology: http://www.ncbi.nlm.nih.gov/pubmed/7854861

The desmosome and the syndesmos: cell junctions in normal development and in malignancy: http://www.ncbi.nlm.nih.gov/pubmed/8983060

Intermediate filaments and the initiation of desmosome assembly: http://www.ncbi.nlm.nih.gov/pubmed/3894376

Related abnormalities

z3288729

Current research methods

z3289066

Current and future possibilities for research

Sarahs idea of z3129413 (me) doing function alright? So i cover ongoing/ future research and function?

Perhaps a collaboration of everyone for every topic, in that everyone submits the key pointers they think the allocated person for that topic should cover.. might lead to a more fluid overall project . I propose we elect a project manager, whom we all argue our cases to of how the project is being directed.

In terms of what a desmosome is and what it does maybe every team member will want a say on how this is portrayed. The project manager can then decide the best possible final content. One person kicks off structure and somebody does function, then individual team members forwards suggestions regarding improvements/ detractions to the project manager . Then the next topic is done. In sequence...might get the project done faster this way.

In this way every topic will become of the group mind. I've read some of the other previous projects and sometimes it looks like four individual projects stapled together.

So someone writes the structure - then we all submit our input to project manager

" ' writes the function - then we all ======================

In this way we know what is being previously said and can follow on....this will be particularly important for the current / ongoing research sections that might become bottle necked here.

The writer of the topic can confer with the group on the discussion page as to what they are writing as they are doing it.

If the writer of the topic disagrees with other group member's ideas the group manager will make a final decision based on a vote.

i dont think it matters who is the group manager but perhaps Sarah is the one for that job (Agree/ Disagree?)


I forward this proposal to the elected project manager and/ or for the group to vote on.

TOPIC BREAKDOWN: Amendment A.

((please comment on ideas of what should be discussed in each topic to give the writer a structure to work with)).

These are my ideas:

1) z3217345 writer: Introduction-Importance of the desmosome in cell biology/who first described the existence of a desmosome? inherited mutations in families first seen / basic necessity of good desmosome function-very brief short description of pathological desmosome function /Structure: location/ histological description/ Em micrographs/ a hand drawn diagram. location of / microscopic appearance which stains are used

2) histological function will be here

3 )z3288729 writer: / abnormalities seen (introduced histologically) factors leading to desmosome pathology is it nutrition based or inherited

4) z3289066 writer: (abnormalities pathology((impact on humans)) leading onto) current research (aims of research/ successes of) what clinical manifestations or symptoms are experienced- the human impact what has research done about it so far

2)+5) z3129413 writer: Histological description of function -introduce the original investigations into desmosome function/ the researchers / due to its structure what is a desmosomes main function includes schematic diagrams and Where research still needs to be done/ any existing problems ( main future investigations of note ). Some sort of conclusion.


writers of topics 1 and 2 will probably have to confer on content.

-z3129413


_____________________________________________________________________________________________________________________________________________

Hi

My name is Sayanthan (Sai) or z3252635 and I'm really sorry I haven't actually said or put up anything on this page. I've read through everything and I'm sort of lost so I was wondering if we could go through the plan in class tommorrow. I've also done a bit of reading up on our topic just background information and sorts so I know what we are talking about. Here are the links i used

Desmosomes

Search for MBoC Desmosomes

Article on Desmosomes In Vivo This may be helpful

Wiki Link

Hemidesmosomes

--Sayanthan Kumaran 23:38, 30 March 2011 (EST)

Working progress

Introduction

M.B

Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis [1]</pubmed>

History

E.K

Historic article on desmosome structue <pubmed>14399189</pubmed> --Sarah Jenkins 10:53, 31 March 2011 (EST)

Structure

M.B

Function

312

Hemidesmosomes

S.K

Necessity for functional desmosomes

<pubmed>20626351</pubmed> --Sarah Jenkins 10:48, 31 March 2011 (EST)

Regulation

E.K

Abnormalities

S.J

<pubmed>20178467</pubmed> --Sarah Jenkins 10:50, 31 March 2011 (EST)

Research Methods and future research

S.K

Glossary

S.J

References

  1. <pubmed>8608588