File:ZFamilial Adenomatous Polyposis.jpg

From CellBiology
Revision as of 20:19, 20 May 2012 by Z3289738 (talk | contribs) (→‎Familial Adenomatous Polyposis (FAP))
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

ZFamilial_Adenomatous_Polyposis.jpg(797 × 269 pixels, file size: 185 KB, MIME type: image/jpeg)

Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis is a hereditary cancer syndrome caused by a germline APC mutation whereby one defective allele is inherited. [1][2] The effect is large numbers of adenomas or polyps (benign out growths) are developed in the colorectum [see picture b]. [3] Inevitably, some of these polyps progress into cancers (CRC) [see picture b and c].


Original text and file name:


"Figure 2 (a) Image showing the entire colon of the third-generation Familial Adenomatous Polyposis (FAP) patient, which was removed by Abdomino Perineal Resection (APR) Method. (b) Image showing the inner lining of the colon, revealing hundreds of polyps all over the surface of the colon and a rosette-shaped malignant tumor at the transverse section of the colon. (c) A close-up of the rosette-shaped malignancy of the colon. The tumor was classified as T4N2M1. Histopathology revealed the tumor to be poorly-differentiated adenocarcinoma."

IJHG-15-143-g002.jpg http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922632/figure/F0002/

Reference

<pubmed>21088721</pubmed>| PMC2922632 | Indian Journal of Genetics


Copyright Information

Indian J Hum Genet. 2009 Sep-Dec; 15(3): 143–144. doi: 10.4103/0971-6866.60192

Copyright © Indian Journal of Human Genetics

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  1. <pubmed>1651562</pubmed>
  2. <pubmed>1651563</pubmed>
  3. Cite error: Invalid <ref> tag; no text was provided for refs named PMID12781368

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current04:16, 13 May 2012Thumbnail for version as of 04:16, 13 May 2012797 × 269 (185 KB)Z3289738 (talk | contribs)Figure 2 (a) Image showing the entire colon of the third-generation Familial Adenomatous Polyposis (FAP) patient, which was removed by Abdomino Perineal Resection (APR) Method. (b) Image showing the inner lining of the colon, revealing hundreds of polyps

The following 2 pages use this file: