File:ZFamilial Adenomatous Polyposis.jpg
ZFamilial_Adenomatous_Polyposis.jpg (797 × 269 pixels, file size: 185 KB, MIME type: image/jpeg)
Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis is a hereditary cancer syndrome caused by a germline APC mutation whereby one defective allele is inherited.  The effect is large numbers of adenomas or polyps (benign out growths) are developed in the colorectum [see picture b].  Inevitably, some of these polyps progress into cancers (CRC) [see picture b/c].
Original text and file name: "Figure 2 (a) Image showing the entire colon of the third-generation Familial Adenomatous Polyposis (FAP) patient, which was removed by Abdomino Perineal Resection (APR) Method. (b) Image showing the inner lining of the colon, revealing hundreds of polyps all over the surface of the colon and a rosette-shaped malignant tumor at the transverse section of the colon. (c) A close-up of the rosette-shaped malignancy of the colon. The tumor was classified as T4N2M1. Histopathology revealed the tumor to be poorly-differentiated adenocarcinoma."
Indian J Hum Genet. 2009 Sep-Dec; 15(3): 143–144. doi: 10.4103/0971-6866.60192
Copyright © Indian Journal of Human Genetics
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Cite error: Invalid
<ref>tag; no text was provided for refs named
Click on a date/time to view the file as it appeared at that time.
|current||04:16, 13 May 2012||797 × 269 (185 KB)||Z3289738||Figure 2 (a) Image showing the entire colon of the third-generation Familial Adenomatous Polyposis (FAP) patient, which was removed by Abdomino Perineal Resection (APR) Method. (b) Image showing the inner lining of the colon, revealing hundreds of polyps|