Difference between revisions of "File:ZFamilial Adenomatous Polyposis.jpg"

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"Figure 2 (a) Image showing the entire colon of the third-generation Familial Adenomatous Polyposis (FAP) patient, which was removed by Abdomino Perineal Resection (APR) Method. (b) Image showing the inner lining of the colon, revealing hundreds of polyps all over the surface of the colon and a rosette-shaped malignant tumor at the transverse section of the colon. (c) A close-up of the rosette-shaped malignancy of the colon. The tumor was classified as T4N2M1. Histopathology revealed the tumor to be poorly-differentiated adenocarcinoma."  
 
"Figure 2 (a) Image showing the entire colon of the third-generation Familial Adenomatous Polyposis (FAP) patient, which was removed by Abdomino Perineal Resection (APR) Method. (b) Image showing the inner lining of the colon, revealing hundreds of polyps all over the surface of the colon and a rosette-shaped malignant tumor at the transverse section of the colon. (c) A close-up of the rosette-shaped malignancy of the colon. The tumor was classified as T4N2M1. Histopathology revealed the tumor to be poorly-differentiated adenocarcinoma."  
  

Revision as of 22:47, 17 May 2012

Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis is a hereditary cancer syndrome caused by a germline APC mutation whereby one defective allele is inherited. [1][2] The effect is large numbers of adenomas or polyps (benign out growths) are developed in the colorectum [see picture b]. [3] Inevitably, some of these polyps progress into cancers (CRC) [see picture b/c].


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"Figure 2 (a) Image showing the entire colon of the third-generation Familial Adenomatous Polyposis (FAP) patient, which was removed by Abdomino Perineal Resection (APR) Method. (b) Image showing the inner lining of the colon, revealing hundreds of polyps all over the surface of the colon and a rosette-shaped malignant tumor at the transverse section of the colon. (c) A close-up of the rosette-shaped malignancy of the colon. The tumor was classified as T4N2M1. Histopathology revealed the tumor to be poorly-differentiated adenocarcinoma."

IJHG-15-143-g002.jpg http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922632/figure/F0002/

Reference

<pubmed>21088721</pubmed>| PMC2922632 | Indian Journal of Genetics


Copyright Information

Indian J Hum Genet. 2009 Sep-Dec; 15(3): 143–144. doi: 10.4103/0971-6866.60192

Copyright © Indian Journal of Human Genetics

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  1. <pubmed>1651562</pubmed>
  2. <pubmed>1651563</pubmed>
  3. Cite error: Invalid <ref> tag; no text was provided for refs named PMID12781368

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current05:16, 13 May 2012Thumbnail for version as of 05:16, 13 May 2012797 × 269 (185 KB)Z3289738 (talk | contribs)Figure 2 (a) Image showing the entire colon of the third-generation Familial Adenomatous Polyposis (FAP) patient, which was removed by Abdomino Perineal Resection (APR) Method. (b) Image showing the inner lining of the colon, revealing hundreds of polyps

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