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Fig. 1. outlines the complexity of signaling in apoptosis, demonstrating how the main forms of signaling are interconnected.
Adapted from images in Wang ZB, Liu YQ, Cui YF. (2005). Pathways to caspase activation. Cell Bio Int. 29:489-496 and Chávez-Galán L, Arenas-Del Angel MC, Zenteno E, Chávez R and Lascurain R. (2009). Cell Death Mechanisms Induced by Cytotoxic Lymphocytes. Cellular & Molecular Immunology. 6(1):15-25
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