File:Yeast NPC.jpg

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Different Views of Yeast Nuclear Pore Complexes (NPCs)

Original file name: 855fig1.jpg

This image depicts the nuclear pore complexes (NPCs) of yeast cells using various imaging techniques.

(a) Transverses sections of the nuclear envelope (NE) using transmission electron microscopy (EM). Large arrows show cytoplasmic filaments, arrowheads point to NPC basket and smaller arrows show the connections between NPCs

(b) Scanning electron microscope images, the top image is an overhead view of NPCs (cytoplasmic side) and bottom image is of the NPC basket (nuclear side)

(c) Cryo-Electron Microscopy map of a yeast NPC showing its density projection

(d) Cryo-Electron Microscopy map of a yeast NPC showing its density contour

(e) Shows the projections of the nucleoporins

(f) Schematic of NPC structure (bottom) and a density contour map obtained through the combined volume of the 456 nucleoporins composing the NPC (top) --Z3331556 (talk) 11:19, 30 May 2013 (EST)

Original legend: Visualizing the yeast NPC. (A) Transmission EM transverse sections of the NE revealing cytoplasmic filamants (large arrows), nuclear baskets (arrowheads), and interbasket connections (small arrows) (Rout and Blobel 1993). (B) Scanning EM showing a bird’s eye view of cytoplasmic filaments (top, arrow) and the nuclear basket (bottom, arrowhead) (Kiseleva et al. 2004). (C) En face slice of the mass density distribution from a cryoEM map of the yeast NPC (Yang et al. 1998). Two equivalent peaks per spoke unit are seen for the outer rings (1–3) and the inner rings (2–4) (see Figure 2). (D) En face surface-rendered view from a cryoEM map of the yeast NPC (Yang et al. 1998). (E) Projections of Nup mass density, derived from the combined Nup localization volumes (Alber et al. 2007b). (F) The structured nucleoporin domains of the NPC, represented by a density contour approximated to the combined volume of the 456 nucleoporins composing the NPC (Alber et al. 2007b).

Reference

<pubmed>PMC3296253</pubmed>

The Yeast Nuclear Pore Complex and Transport Through It

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296253/

Copyright

Copyright © 2012 by the Genetics Society of America

Available freely online through the author-supported open access option.

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current11:53, 30 May 2013Thumbnail for version as of 11:53, 30 May 2013448 × 985 (242 KB)Z3331556 (talk | contribs)Original file name: 855fig1.jpg The Yeast Nuclear Pore Complex and Transport Through It http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296253/ Visualizing the yeast NPC. (A) Transmission EM transverse sections of the NE revealing cytoplasmic filamants...
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