File:Possible membrane sources of isolation membrane.png
Possible_membrane_sources_of_isolation_membrane.png (600 × 338 pixels, file size: 50 KB, MIME type: image/png)
Possible Membrane Sources of the isolation membrane
Some of the possible scenarios for IM formation are illustrated here. According to the maturation model, upon induction of autophagy, membrane may be directly derived from the ER by folding (A), or in the form of vesicular transport (B). In the assembly model, membrane may be assembled de novo at the site of IM formation, originating from nonvesicular transport, such as micellar, as shown in (C), or local synthesis (D). See text for further details.
Figure 2. Journal.pbio.0040036.g002.png
Abbreviations: Atg, autophagy-related gene; ER, endoplasmic reticulum; IM, isolation membrane; PAS, preautophagosomal structure
Citation: Juhasz G, Neufeld TP (2006) Autophagy: A Forty-Year Search for a Missing Membrane Source. PLoS Biol 4(2): e36. doi:10.1371/journal.pbio.0040036
Published: February 14, 2006
Copyright: © 2006 Juhasz and Neufeld. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in ay medium, provided the original author and source are credited.
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|current||08:08, 10 May 2011||600 × 338 (50 KB)||S8600021||==Possible Membrane Sources of the isolation membrane== Some of the possible scenarios for IM formation are illustrated here. According to the maturation model, upon induction of autophagy, membrane may be directly derived from the ER by folding (A), or|