Original file (1,234 × 796 pixels, file size: 100 KB, MIME type: image/gif)
This image illustrates the polymeric method. It shows the primary antibody which is applied to the tissue section, and the polymeric conjugates which are made up of a dextran backbone. Secondary antibodies and peroxidase binds onto this conjugate.
The EnVision++ system: a new immunohistochemical method for diagnostics and research. Critical comparison with the APAAP, ChemMate, CSA, LABC, and SABC techniques. Sabattini E, Bisgaard K, Ascani S, Poggi S, Piccioli M, Ceccarelli C, Pieri F, Fraternali-Orcioni G, Pileri SA. J Clin Pathol. 1998 Jul;51(7):506-11. 
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