File:Nuclear envelope during mitosis.jpg

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Revision as of 16:51, 7 April 2013 by Z3331556 (talk | contribs) (Original file name: 1423-0127-16-96-3.jpg The nuclear envelopathies and human diseases http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770040/ Nuclear envelope breakdown and reassembly in mitosis. At the end of G2, the activation of cyclin-dependent ki...)
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Original file name: 1423-0127-16-96-3.jpg

The nuclear envelopathies and human diseases

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770040/

Nuclear envelope breakdown and reassembly in mitosis. At the end of G2, the activation of cyclin-dependent kinases, including CDK1, triggers entry into mitotic prophase. The nuclear membrane breaks down, and the NE-associate proteins either translocate to kinetochores, distribute with the fragmented ER networks, or dissolve in the cytoplasm. During NE reassembly in anaphase, SUN1 and LAP2 first appear around the condensed chromatin, though at different regions. The nuclear lamins then join the nuclear periphery in telophase. This figure illustrates the important roles played by the NE and the nuclear lamina in normal mitosis.

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current16:51, 7 April 2013Thumbnail for version as of 16:51, 7 April 2013600 × 395 (50 KB)Z3331556 (talk | contribs)Original file name: 1423-0127-16-96-3.jpg The nuclear envelopathies and human diseases http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770040/ Nuclear envelope breakdown and reassembly in mitosis. At the end of G2, the activation of cyclin-dependent ki...
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