File:Nuclear envelope and its proteins.jpg

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Original file name: 1423-0127-16-96-1.jpg

The nuclear envelopathies and human diseases

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770040/

The three-layers of NE proteins. The nuclear pore complex (NPC) transverses the inner and outer nuclear membranes. INM proteins, including SUN1, LAP2, Emerin, MAN1 and LBR, are mostly associated with the nuclear lamina. Emerin, LAP2 and MAN1 harbor a LEM domain which interacts with BAF (barrier-to-autointegration factor), a chromatin-binding protein. The nuclear lamina forms a meshwork underlying the inner nuclear membrane.

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current13:10, 7 April 2013Thumbnail for version as of 13:10, 7 April 2013600 × 361 (56 KB)Z3331556 (talk | contribs)Original file name: 1423-0127-16-96-1.jpg The nuclear envelopathies and human diseases http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770040/ The three-layers of NE proteins. The nuclear pore complex (NPC) transverses the inner and outer nuclear membr...
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