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Expression of early lineage markers in morulae and blastocysts

Laser scanning confocal (A–C) and fluorescent microscopic (D–E) analysis revealed expression of Oct4 in all cells of the morula and primarily in the ICM of the blastocyst (A, D, and E; red), Cdx2 in all cells of the morula and exclusively in the trophectoderm of the blastocyst (B–E; green), and Nanog in most but not all cells of the ICM at the blastocyst stage (C; red). Nuclei were stained with DAPI (A and B; blue).

Fig. 4. F4.large.jpg http://www.pnas.org/content/102/23/8239/F4.large.jpg

Reference

<pubmed>15917331</pubmed>| PNAS

Proceedings National Academy of Sciences (PNAS) Liberalization of PNAS copyright policy: Noncommercial use freely allowed Note original Author should be contacted for permission to reuse for Educational purposes. See also PNAS Author Rights and Permission FAQs

Cozzarelli NR, Fulton KR, Sullenberger DM. Liberalization of PNAS copyright policy: noncommercial use freely allowed. Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12399. PMID15314225 "Our guiding principle is that, while PNAS retains copyright, anyone can make noncommercial use of work in PNAS without asking our permission, provided that the original source is cited."

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