File:Elastic fiber formation.jpg

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Revision as of 17:21, 23 April 2015 by Z3374116 (talk | contribs) (Role of MFAP-4 in Elastic fiber formation (a) Secreted MFAP-4 and fibrillin-1 interact directly, resulting in the assembly of microfibrils under normal conditions. Tropoelastins assembled with LOX recruited by fibulin-4 are subsequently cross-linked w...)
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Role of MFAP-4 in Elastic fiber formation

(a) Secreted MFAP-4 and fibrillin-1 interact directly, resulting in the assembly of microfibrils under normal conditions. Tropoelastins assembled with LOX recruited by fibulin-4 are subsequently cross-linked with microfibrils for the formation of complete mature elastic fibers. (b) In the absence of MFAP-4, fibrillin-1 cannot be assembled or matured for the formation of microfibrils. Tropoelastins are never cross-linked due to the failure of microfibril formation.

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current17:21, 23 April 2015Thumbnail for version as of 17:21, 23 April 2015946 × 624 (103 KB)Z3374116 (talk | contribs)Role of MFAP-4 in Elastic fiber formation (a) Secreted MFAP-4 and fibrillin-1 interact directly, resulting in the assembly of microfibrils under normal conditions. Tropoelastins assembled with LOX recruited by fibulin-4 are subsequently cross-linked w...

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