Difference between revisions of "File:Calpain superfamily members.jpg"

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(Schematic structures of calpain superfamily members Calpain homologues have been identified in vertebrates, insects, nematodes, schistosomes, trypanosomes, plants, fungi, yeasts, some bacteria etc. Symbols used are; I: the N-terminal domain with little)
 
 
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Schematic structures of calpain superfamily members  
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==Schematic structures of calpain superfamily members ==
  
  
Calpain homologues have been identified in vertebrates, insects, nematodes, schistosomes, trypanosomes, plants, fungi, yeasts, some bacteria etc. Symbols used are; I: the N-terminal domain with little homology; IIa and IIb: the protease sub-domains containing the active sites Cys, and His, respectively; III: the C2-like Ca2+-binding domain; III’ and III’’: domains moderately and very weakly similar to the domain III, respectively; IV and VI: the 5-EF-hand Ca2+-binding domain; V: Gly-rich hydrophobic domain; NS, IS1, and IS2: p94-specific sequences; T: TRA-3 subfamily-specific C2 domain; MIT: Microtubule-interacting and trafficking domain; Zn: Zn-finger motif containing domain; SOH: SOL subfamily homology domain; DIS: CALPA-specific insertion sequence; TM: transmembrane domain; CSTN: the domain weakly similar to calpastatin.
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Calpain homologues have been identified in vertebrates, insects, nematodes, schistosomes, trypanosomes, plants, fungi, yeasts, some bacteria etc.  
 +
 
 +
Symbols used
 +
* I: the N-terminal domain with little homology
 +
* IIa and IIb: the protease sub-domains containing the active sites Cys, and His, respectively
 +
* III: the C2-like Ca2+-binding domain
 +
* III’ and III’’: domains moderately and very weakly similar to the domain III, respectively
 +
* IV and VI: the 5-EF-hand Ca2+-binding domain
 +
* V: Gly-rich hydrophobic domain
 +
* NS, IS1, and IS2: p94-specific sequences
 +
* T: TRA-3 subfamily-specific C2 domain
 +
* MIT: Microtubule-interacting and trafficking domain
 +
* Zn: Zn-finger motif containing domain
 +
* SOH: SOL subfamily homology domain
 +
* DIS: CALPA-specific insertion sequence
 +
* TM: transmembrane domain;  
 +
* CSTN: the domain weakly similar to calpastatin.
  
 
Fig. 1. http://calpain.org/overview.rb?cls=calpain
 
Fig. 1. http://calpain.org/overview.rb?cls=calpain
  
 
Reproduced for educational purposes.
 
Reproduced for educational purposes.

Latest revision as of 09:51, 10 May 2011

Schematic structures of calpain superfamily members

Calpain homologues have been identified in vertebrates, insects, nematodes, schistosomes, trypanosomes, plants, fungi, yeasts, some bacteria etc.

Symbols used

  • I: the N-terminal domain with little homology
  • IIa and IIb: the protease sub-domains containing the active sites Cys, and His, respectively
  • III: the C2-like Ca2+-binding domain
  • III’ and III’’: domains moderately and very weakly similar to the domain III, respectively
  • IV and VI: the 5-EF-hand Ca2+-binding domain
  • V: Gly-rich hydrophobic domain
  • NS, IS1, and IS2: p94-specific sequences
  • T: TRA-3 subfamily-specific C2 domain
  • MIT: Microtubule-interacting and trafficking domain
  • Zn: Zn-finger motif containing domain
  • SOH: SOL subfamily homology domain
  • DIS: CALPA-specific insertion sequence
  • TM: transmembrane domain;
  • CSTN: the domain weakly similar to calpastatin.

Fig. 1. http://calpain.org/overview.rb?cls=calpain

Reproduced for educational purposes.

File history

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current09:48, 10 May 2011Thumbnail for version as of 09:48, 10 May 20111,000 × 923 (215 KB)S8600021 (talk | contribs)Schematic structures of calpain superfamily members Calpain homologues have been identified in vertebrates, insects, nematodes, schistosomes, trypanosomes, plants, fungi, yeasts, some bacteria etc. Symbols used are; I: the N-terminal domain with little

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