File:Bacterial and Eukaryotic Microtubule Structure.png
Structural Model of Bacterial and Eukaryotic Microtubules
This picture depicts the similarities and differences between the structures of bacterial microtubules (blue) and their eukaryotic counterparts (grey). Bacterial microtubules share features with their eukaryotic counterparts such as straight protofilaments and similar protofilament interactions. They are however only composed of 5 protofilaments whereas eukaryotic microtubules are usually composed of 13.
Figure 4. Structural model of “bacterial microtubules.”
(A) 2-D schematic of the proposed architecture of bacterial microtubules built from BtubA (dark-blue) and BtubB (light-blue). Protofilaments are numbered 1–5. (B) 3-D comparison of the architectures of a bacterial microtubule (left; BtubA in dark-blue; BtubB in light-blue) and a 13-protofilament eukaryotic microtubule (right; β-tubulin in black; α-tubulin in white). Seams and start-helices are indicated as in (A). doi:10.1371/journal.pbio.1001213.g004
Pilhofer M, Ladinsky MS, McDowall AW, Petroni G, Jensen GJ (2011) Microtubules in Bacteria: Ancient Tubulins Build a Five-Protofilament Homolog of the Eukaryotic Cytoskeleton. PLoS Biol 9(12): e1001213. doi:10.1371/journal.pbio.1001213
© 2011 Pilhofer et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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