2011 Group 2 Project

From CellBiology

Introduction

Haley

History

Michael

Structure

Michael

Function

Haley

Location

Hadassah

Gap Junctions are located in cardiac muscle and smooth muscle

==Comparison with Other Junctions==

Hadassah

Comparison of Cell Junctions
Name of Junction Function Location Associated Proteins Diseases Diagram
Tight Junction Form a barrier which holds neighbouring cells together

preventing the mixing of apical and basolateral components helping to maintain cell polarity [1]

Apical junction of epithelial cells and endothelial cells [2] occludin

claudins junction adhesion molecules [3]

Inflammatory Bowel Disease (IBD)

Crohn's Disease and Ulcerative Colitis associated with loss of tight junction [4]

Neuromuscular Junction Invloved in communcation and muscle contraction Smooth and Skeletal muscle fibres Myasthenia Gravis

Botulism

Diseases Associated with Gap Junctions

Liz

Current Research

Liz

Glossary

References

  1. <pubmed> 9454728 </pubmed>
  2. <pubmed> 9454728 </pubmed>
  3. <pubmed> 15151915 </pubmed>
  4. <pubmed> 19632896 </pubmed>


2011 Projects: Synaptic Junctions | Gap Junctions | Tight Junctions | Desmosomes | Adherens Junctions | Neuromuscular Junction