2009 Lecture 5

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Cell Export - Exocytosis

This lecture introduces how information is transferred from stable stored information (DNA) converted to an intermediate (mRNA, rRNA, tRNA) of variable stability, exported from the nucleus to the cytoplasm where mRNA is then translated into Protein. This is gene expression, the products of this process are used either within the cell, exported (exocytosis) or used to replace worn out components.

We will study this topic at the level of the cellular components and organelles involved in the process: ribosomes, endoplasmic reticulum, Golgi apparatus, vesicles (transport and secretory).


Objectives

  • Brief understanding of gene expression
  • Understanding structure and function of organelles and structures associated with protein export (exocytosis)
    • ribosome
    • endoplasmic reticulum
    • vesicles - types and transport
    • Golgi apparatus structure and function
  • Brief understanding of transport between secretory compartments