From CellBiology
  • It is very informative but i think there is too much information. One of the guidelines were The final project should not be too lengthy, as a guideline typically 500 to a maximum of 1000 words. Maybe consider cutting some parts out... Also, the first part looks good with the images and table but the bottom half is text heavy... and the table has no 'source', 'based on' or any copyright information...


  1. Your content at the start is very clear and concise, however under your subheading for Troponin as a biomarker - you could make it look simpler by putting dot points in it.

You could try to include the morphological aspects of necrosis. And you can try to put more images on the lower half of your report, looks a bit dull in the lower half.

1.z3217578: I think that if you're going to include a conclusion section that you should write more in it, otherwise maybe leave it out?

You have now created your individual project page. Very well done good use of tables. I also enjoyed the creative intro.

2. I couldn't find a link back to your group page. is it there? your layout is good but i think you could separate the page a little better so it is clearer to follow down the page. i was also wondering why you haven't referenced your intro.(Beatrix z3158969)

3. There is indeed a great amount of general information regarding the topic of detecting necrosis by Tropinin. It is clear that you have created a basic tabulated summary of differences of troponin through the application of the knowledge regarding the your area of study. Another aspect of your project that is quite appealing is the addition of Limitations through the methods as it would be an excellent area that would not have been included in other Method projects. The conclusion of your report does appear to be quite short and brief, perhaps it could be included into another subtopic of your project or elaborate a few more words of the matter. -z3224479

4. the content seems to be well researched and a lot of useful information is relayed. however, it would be great to have additional pictures to support your text as it may look very daunting with big chunks of just text. it may also help if you separate parts in different paragraphs and subheadings. it is a very good work here!

5. I have a sneaky suspiscion that table 1 is scanned in from a molecular biology lab book... if this is the case, should it not be referenced? --Peter Kehoe 22:58, 21 May 2009 (EST)

6. Hi there, interesting topic! you have done a very good job. But few suggestions: 1-interlink your entry to your group project. 2-you have a diagram of Cardiac Necrosis, I was wondering if you could also provide a photo of a healthy cardiac cell, just that’d make the contrast. 3-glossary normally helps but in your case I found the text pretty well and clearly described. Btw, I really like the table where you have summarized different Troponins and their function. Well done! Z3191358

7. I agree that your page is too lengthy and suggest some culling to take place. Love the inclusion of the table on your page, simple but effective. Cause and effect are well explained in the text. good job overall!

8. Hi, your work has a good flow, is well written and very infromative. It is clear you have done a lot of research. I like the limitations section as well but I think Peter Kehoe is right about the table .. ?? Hehe. Overall good job. --Jessica Lazarus 19:12, 24 May 2009 (EST)

Pages that I have peer-reviewed:

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--Mark Hill 09:55, 20 April 2009 (EST) Lecture 10 - What is the name of the epidermal layer between the basal and granulosa layer and how does it relate to intermediate filaments? And your indidual project topic?

--Mark Hill 18:32, 19 March 2009 (EST)You still need to provide feedback for Lecture 4 - Nucleus.

--Mark Hill 20:27, 23 March 2009 (EST) Thank you for your feedback on the Nucleus lecture. I always try and include an example of a human disorder in each of the lectures, to show the relevance of the topic to basic and clinal research. I find it interesting that a single protein can have such major ramifications to human health.

--Mark Hill 07:44, 25 March 2009 (EST)Thank you for your feedback. Try and get your spelling grammar correct (excytosis = Exocytosis), it shows you have checked your work. Yes constitutive vs regulated secretion are difficult concepts, I did not go into details about how regulation occurs, but gave an example of changing calcium (a key signaling molecule/ion within cells) levels being at least one mechanism. Did you also know that the ER is an important calcium store within the cell. This may help with the Golgi The Golgi Cisternae Are Organized as a Series of Processing Compartments

Correct definitions for CAM terms, lots of science today uses acronyms (because the terms or gene names are very long), but what this can mean is that several acronyms can mean different things to different people.

Comment on Lecture 4: The Nucleus

I found the part on Nuclear Lamins interesting, particularly how a point mutation in the gene encoding for lamin A and lamin C can lead to a deformed nucleus, resulting in Hutchison-Gilford Progeria Syndrome. This genetic condition is marked by rapid aging in early childhood.

Comment on Lecture 5: Exocytosis

What I found difficult about the concept of exocytosis:

I am yet to fully grasp constitutive vs regulated secretion and the structure of the golgi apparatus (stacks and cisternae) in relation to its function.

Lecture 7 Homework

Cellular processes that require energy include:

  • biosynthesis
  • signal transmission
  • active transport of molecules across cell membranes
  • locomotion / mechanical work eg muscle contraction; to power flagella

Lecture 8 Homework

  • Ng-CAM: Neural glial cell adhesion molecule
  • L-CAM: Liver cell adhesion molecule
  • I-CAM: Intercellular adhesion molecule

Lecture 10 Homework

What is the name of the epidermal layer between the basal and granulosa layer and how does it relate to intermediate filaments?

Stratum Spinosum

Cells of the stratum spinosum synthesis intermediate filaments called cytokeratins. Attached to desmosomes they join adjacent cells and in this way provide structural support.

Lecture 14 Homework: Confocal Microscopy

The 2 main forms of generating confocal microscopy are:

  • Laser
  • Spinning disc

Lecture 15 Homework: Cell Cycle

The "S" in the S phase of the cell cycle stands for 'synthesis'. During this phase DNA duplication occurs which normally takes 10-12 hours.