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13:46, 28 November 2017 MT and MF movements.mp4 (file) 4.4 MB Z8600021 The precise coupling of f-actin and parallel MT movements occurrs in all four zones of f-actin dynamic behavior: the lamellipodium,lamellum, convergence zone, and cell body. Primary cultures of newt (Taricha granulosa) lung epithelial cells were microi... 1
13:31, 28 November 2017 Microtubule - spindle formation.mp4 (file) 386 KB Z8600021 Time lapse movie of a porcine kidney LLCPK1 cell stably expressing EGFP-alpha tubulin. The movie shows microtubule behavior from early prophase through metaphase. ==Microtubule - Spindle Formation== Cells were imaged using a Nikon Eclipse TE300 micros... 1
16:29, 23 November 2017 Pre-Medicine Program 2017 - Cell Compartments and Membranes.pdf (file) 2.78 MB Z8600021 Pre-Medicine Program 2017 - Cell_Compartments_and_Membranes.pdf 1
16:29, 23 November 2017 Pre-Medicine Program 2017 - Cell Filament Systems.pdf (file) 4.34 MB Z8600021 Pre-Medicine Program 2016 - Cell_Filament_Systems.pdf 1
16:28, 23 November 2017 Pre-Medicine Program 2017 - Cell Export and Import.pdf (file) 2.18 MB Z8600021   1
11:51, 31 May 2017 Proposed Hox protein classification.jpg (file) 126 KB Z8600021 ==Proposed Hox Protein Classification== The organisms are ordered to show the clearest representation of the Hox-proteins most similar in sequence and thus expected to be most similar in function. The figure is not supposed to indicate that Drosophi... 1
16:30, 26 May 2017 Pancreas Drawings.png (file) 10.7 MB Z5158862   1
12:28, 26 May 2017 Pancreas development.JPG (file) 39 KB Z5076777 ==Title== caption ===Reference=== <pubmed>19013144</pubmed> ====Copyright==== Articles published under an Elsevier user license are protected by copyright. Users may access, download, copy, translate, text and data mine (but may not redistribute, di... 1
11:31, 26 May 2017 Effect of Glibenclamide on Diabetes.JPG (file) 112 KB Z5076777 ==The therapeutic effect of glibenclamide on NOD mice== A. compared microscopic histological staining of pancreatic islets before and after the treatment of glibenclamide. The images highlight the substantial increase of islet number and size after dos... 1
09:24, 26 May 2017 Signalling of beta-cell.JPG (file) 47 KB Z5076777 ==Title== caption ===Reference=== <pubmed>16464129</pubmed> ====Copyright==== Copyright: © 2006 MacDonald and Rorsman. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestrict... 1
09:14, 26 May 2017 Microscopic structure of pancreas.JPG (file) 35 KB Z5076777 ==Microscopic structure of pancreas== This image depicts the Islets of Langerhans surrounded by the adjacent clusters of digestive enzyme secreting acinar cells in the darker stained pink. Also depicted in the image are the blood vessels and ducts with... 1
08:39, 26 May 2017 Electron transport chain(2).JPG (file) 74 KB Z5076777 ==Title== caption ===Reference=== <pubmed>20346106</pubmed> ====Copyright==== © Brockington et al; licensee BioMed Central Ltd. 2010 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under th... 1
00:33, 26 May 2017 Hedgehog pathways.jpg (file) 117 KB Z3429175 ==Hedgehog Signaling Pathway== HH ligands (SHH, DHH or IHH) attach to the PTCH1 and PTCH2 and reduce the inhibition of SMO. HHIP which is a negative inhibitor of HH signaling, is able to compete with PTCH receptors to bind HH ligand. Therefore, it lea... 1
23:29, 25 May 2017 Interconnected murine islets.png (file) 1.12 MB Z5075505 This image shows an elongated cord-like structure of islet cells prior to fission into spherical islet structures. α-cells are stained red and β-cells are stained green. ==Reference== <pubmed>19893748</pubmed> © 2009 Miller et al. This is an open... 1
22:12, 25 May 2017 Hormone homeostasis.png (file) 445 KB Z5075505 ==Reference== Adapted from Fang-Xu Jiang and Grant Morahan (2011). Pancreatic Stem Cells: Unresolved Business, Stem Cells in Clinic and Research, Dr. Ali Gholamrezanezhad (Ed.), InTech, DOI: 10.5772/23760. Available from: https://www.intechopen.com/bo... 1
19:37, 25 May 2017 ZHhex Expression in Mouse and Human Pancreas.jpeg (file) 158 KB Z5016456 ==Hhex Expression in Mouse and Human Pancreas== ===Description=== Hhex expression in the adult mouse and human pancreas. '''A'''Immunofluorescent labeling of an adult mouse pancreas reveals robust Hhex expression in Sst-producing δ cells. Hhex imm... 1
18:39, 25 May 2017 SstGhsr.png (file) 591 KB Z3429175 ==Ghsr is specifically expressed in δ-cells== D: FISH supporting the expression of Ghsr gene (green dots) in pancreatic delta cells of wild type mice, colocalized with Sst message (red dots) and also Sst peptide (white). E: mRNA for Ghsr (green dot... 1
16:45, 25 May 2017 Effect of pig embryonic pancreatic tissue transplant.JPG (file) 27 KB Z5076777 ==Effect of varying stages of pig embryonic pancreatic tissue transplantation in diabetic mice== This study utilised varying gestational periods of pig pancreatic tissue to transplant into diabetic mice and found the embryonic tissue from the 42nd emb... 1
14:57, 25 May 2017 Pancreatic islet transplantation.JPG (file) 40 KB Z5076777 ==Procedure of islet transplanration depicted diagrammatically== Transplants often are performed through the use of ultrasound to guide a catheter; a small plastic tube through the upper abdomen and into the portal vein of the liver. Islets are then i... 1
12:37, 25 May 2017 Evolution of beta-cell dysfunction.JPG (file) 30 KB Z5076777   1
12:02, 25 May 2017 Effect of Adrenomedulin on Insulin Secretion.JPG (file) 16 KB Z5076777   1
12:02, 25 May 2017 ZHistology of Diabetic Islets.png (file) 1.01 MB Z5016456 ==Histology of Diabetic Islets== ===Description=== Hyaline deposits and degeneration in pancreatic islets visible in this microscopic H&E stained slide of a human pancreas from a type 1 diabetic. ===Reference=== Prof James Fishback, Department of... 1
10:21, 25 May 2017 ZMacro and Microscopic Appearance of Pancreatic Neuroendocrine Tumour.png (file) 391 KB Z5016456 ==Macro and Microscopic Appearance of Pancreatic Neuroendocrine Tumour== ===Description=== '''A:''' Macroscopic appearance of pancreatic neuroendocrine tumour showing a well-demarcated pinkish tumour surrounded by normal pancreatic parenchyma. '''B:... 1
03:43, 25 May 2017 Pancreas drawings.png (file) 10.16 MB Z5158862   1
01:16, 25 May 2017 Delta cell granules in human islet.jpg (file) 86 KB Z5075505 This electron micrograph shows the granular structure of δ-cells denoted by the 'δ' symbol. Note that δ-cell granules do not possess a halo like β-cells. They are visibly less dense than α- and β-cell granules. ==Reference== <pubmed>20697378</p... 1
01:10, 25 May 2017 Human islet compositionmerged.tif (file) 466 KB Z5075505 This image shows the granular structure of δ-cells denoted by the 'δ' symbol. Note that δ-cell granules do not possess a halo like β-cells. They are less dense relative to α- and β-cell granules. ==Reference== <pubmed>20697378</pubmed> Permis... 1
23:08, 24 May 2017 Screen Shot 2017-05-24 at 10.02.38 PM.png (file) 391 KB Z5016456 ==Macro and Microscopic Appearance of Pancreatic Neuroendocrine Tumour== ===Description=== '''A:''' Macroscopic appearance of pancreatic neuroendocrine tumour showing a well-demarcated pinkish tumour surrounded by normal pancreatic parenchyma. '''B:... 1
22:40, 24 May 2017 ZMacro and Microscopic Appearance Pancreatic Adenocarcinoma.jpeg (file) 126 KB Z5016456 ==Macro and Microscopic Appearance Pancreatic Adenocarcinoma== ===Description=== '''A:''' Macroscopic appearance of a pancreatic ductal adenocarcinoma showing a poorly demarcated firm white tumor in the pancreatic parenchyma (T=Tumor, P=pancreatic pa... 1
21:45, 24 May 2017 GPR120 localisation.gif (file) 72 KB Z5075505 This image shows the localisation of GPR120 receptors exclusively on δ-cells in murine pancreatic islets. GPR120 receptors are indicated in red, stained for β-galactosidase as a surrogate for the receptor. ==Reference== <pubmed>24663807</pubmed>... 1
12:48, 24 May 2017 Opposing actions of PAX4 and ARX.PNG (file) 242 KB Z5075505 In wild-types (A) with normal expression of PAX4 and ARX, the two factors are mutually corepressive. In ARX gene knockouts (B), the factor is no longer able to repress PAX4 action, leading to excessive proliferation of the δ-cells in its lineage. ARX... 1
01:04, 24 May 2017 Pancreatic Anatomy Comparison.png (file) 374 KB Z5061522 ==Title== Anatomical comparison of the human pancreas (A) and mouse pancreas (B). Human pancreas depicts a head, body, and tail portion whereas the mouse pancreas showcases 3, less well-defined lobes: the duodenal, the gastric, and the splenic lobe.... 1
23:32, 23 May 2017 SST-14.png (file) 10 KB Z5075505 A two-dimensional representation of Somatostatin-14 (SST-14). This compound can also be described with its molecular formula C76H104N18O19S2 or in IUPAC form as "H-DL-Ala-Gly-DL-Cys(1)-DL-Lys-DL-Asn-DL-Phe-DL-Phe-DL-Trp-DL-Lys-DL-xiThr-DL-Phe-DL-xiThr-... 1
21:56, 23 May 2017 Delta-cell distribution in human islet.png (file) 10.29 MB Z5075505 Image A shows the distribution of δ-cells (blue) across a human islet immunostained for insulin (red), glucagon (green) and somatostatin (blue). Image B shows δ-cells in isolation. Note: this image was cropped and edited together from a complete im... 1
21:20, 23 May 2017 ZHistology of Pancreatic Islets.png (file) 743 KB Z5016456 ==Histology of Pancreatic Islets== ===Description=== '''A:''' Bright field microscopic slide of a human pancreatic islet stained with H&E. Surrounding acini can be staining slightly darker in colour, with a faint outline of islet visible. Cells withi... 1
21:17, 23 May 2017 Structural variation of pancreatic islets across species.jpg (file) 120 KB Z5075505 These are confocal micrographs of human (A), monkey (B), mouse (C) and pig (D) pancreatic islets, highlighting the structural differences across species. Human and monkey islets display random organisation of α-cells (green), β-cells (red) and δ-cel... 1
21:04, 23 May 2017 Proximity of Delta-cells to intra-islet vessels.jpeg (file) 70 KB Z5075505 β-cells are shown in red, α-cells in green and δ-cells in cyan, stained for insulin, glucagon and somatostatin respectively. Vascular smooth muscle cells and endothelial cells are shown in blue. Note that all endocrine cell types are in contact with... 1
15:34, 23 May 2017 Fluorescent EM Showcasing Insulin.png (file) 152 KB Z5061522   1
15:27, 23 May 2017 Fluorescent EM showcasing Proinsulin.png (file) 127 KB Z5061522   1
13:07, 23 May 2017 Islets of Langerhans - alpha cell.jpg (file) 22 KB Z3465108 Islets of Langerhans consist of secretory cells; alpha, beta, delta and pancreatic polypeptide cells. Each produce hormones for nutrient regulation as well as regulation of these paracrine secretions through cell to cell interactions. 1
04:19, 23 May 2017 Micro 2.png (file) 328 KB Z5019526   1
04:18, 23 May 2017 Macro 1.png (file) 499 KB Z5019526   1
01:19, 23 May 2017 Beta Cells Title Image.png (file) 403 KB Z5061522 This image was created by user z5061522 for the purpose of the present page. The image uses a photomicrograph of insulin immunohistochemical staining of pancreatic islets. Reference: A histological and immunohistochemical study of beta cells in stre... 1
23:23, 22 May 2017 Location of alpha cells in islet of langerhans.jpg (file) 445 KB Z3329177 Zdb0050957290007.jpg https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671059/ Anatomical location within the pancreas determines the endocrine cell fate during diabetes development. Consecutive sections of one naïve (A–D) and one newly diabetic (E–L)... 1
22:54, 22 May 2017 Structure of islet of langerhans.jpg (file) 58 KB Z3329177 Zdb0050957290001.jpg https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671059/ Pancreatic islet hormone-secreting cell subsets as assessed by immunofluorescence and flow cytometry. A: Pancreas section from a naïve C57BL/6 mouse simultaneously stained for... 1
21:16, 22 May 2017 Endocrine and Paracrine interactions within Islets of Langerhans.png (file) 1.79 MB Z5075505 This image shows the interaction between Beta-cells (β), Alpha-cells (α) and Delta-cells (𝛿) within pancreatic islets. As described by the image authors, the blue arrows represent negative effects while the red arrows represent positive effects. N... 1
15:03, 22 May 2017 Ghrelin Calcium.png (file) 295 KB Z3429175 ==Ghrelin potentiates GSSS== A: The responses of calcium were calculated for a period of time in intact islets using the genetically encoded calcium sensor GCaMP6 expressed particularly in delta cells. Calcium traces of two indicative cells in respons... 1
12:18, 21 May 2017 Alpha cell development .png (file) 157 KB Z5059696 Own diagram of alpha cell development over embryonic days. Based on information from the source <pubmed>20035712</pubmed> {{Student Image}} 1
20:28, 20 May 2017 Structural organization of duct cells.png (file) 132 KB Z5019526   1
14:30, 20 May 2017 Pancreatic lineages in the mouse..jpg (file) 58 KB Z5059696 Pancreatic Lineages in the Mouse Pancreas specification within the foregut endoderm is first indicated by expression of the transcription factor Pdx1, which marks the progenitors of all exocrine and endocrine cell types. As the embryonic organ grows,... 1
12:09, 20 May 2017 Histology of Acute Pancreatitis.png (file) 539 KB Z5129708 Histology of acute pancreatitis - late acute pancreatitis in Mice tissue. <pubmed>25470824</pubmed> Copyright notice This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted u... 1
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