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Microtubules - The Basics

Microtubules are non-covalent cytoskeletal polymers found in all eukaryotic cells that are involved in mitosis, cell motility, intracellular transport, secretion, the maintenance of cell shape and cell polarization. They are polarized structures composed of - and -tubulin heterodimer subunits assembled into linear protofilaments. A single microtubule is comprised of 10–15 protofilaments (usually 13 in mammalian cells) that associate laterally to form a 24 nm wide hollow cylinder

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Reference

Microtubule assembly, organization and dynamics in axons and dendrites. Conde C, Cáceres A. Nat Rev Neurosci. 2009 May;10(5):319-32. Review. PMID: 19377501


Reprinted by permission from Macmillan Publishers Ltd: [Nature Reviews Neuroscience] (Microtubule assembly, organization and dynamics in axons and dendrites. Conde C, Cáceres A. Nat Rev Neurosci. 2009 May;10(5):319-32. Review. PMID: 19377501), copyright (2009)


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current15:35, 16 November 2010Thumbnail for version as of 15:35, 16 November 2010655 × 527 (61 KB)S8600021 (talk | contribs)==Microtubules - The Basics== Microtubules are non-covalent cytoskeletal polymers found in all eukaryotic cells that are involved in mitosis, cell motility, intracellular transport, secretion, the maintenance of cell shape and cell polarization. They are
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