Endosome Movie 1
| SBD is a non-toxic probe consisting of a 25-amino acid sphingolipid binding domain, the SBD, derived from the amyloid peptide Abeta, and conjugated by a neutral linker with an organic fluorophore. SBD was the name given to a motif originally recognized by Fantini et al in a number of glycolipid-associated proteins, and was proposed to interact with sphingolipids in membrane microdomains.
Steffen Steinert, Esther Lee, Guillaume Tresset, Dawei Zhang, Ralf Hortsch, Richard Wetzel, Sarita Hebbar, Jeyapriya Raja Sundram, Sashi Kesavapany, Elke Boschke, Rachel Kraut A fluorescent glycolipid-binding peptide probe traces cholesterol dependent microdomain-derived trafficking pathways. PLoS ONE: 2008, 3(8);e2933 PubMed 18716682
Copyright: © 2008 Steinert et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Citation: Steinert S, Lee E, Tresset G, Zhang D, Hortsch R, et al. (2008) A Fluorescent Glycolipid-Binding Peptide Probe Traces Cholesterol Dependent Microdomain-Derived Trafficking Pathways. PLoS ONE 3(8): e2933. doi:10.1371/journal.pone.0002933
Original File name: Journal.pone.0002933.s004.mov
Dr Mark Hill 2015, UNSW Cell Biology - UNSW CRICOS Provider Code No. 00098G