UNSW Cell Biology

2008 ANAT3231 Lecture 12 - 13 Extracellular Matrix

Introduction

These lectures introduces Extracellular Matrix, current slides are now linked below. Lecture 12-13: PDF 2008 lecture12-13 1 slide/page (view only) (55 pages, 1.5 Mb) PDF 2008 lecture12-13 4 slides/page (print) (14 pages, 740 Kb) PDF 2008 lecture12-13 6 slides/page (print) (7 pages, 711 Kb) PDF 2008 lecture12-13 slides text (print) (7 pages, 132 Kb)	Scanning EM of Collagen Fibers     Notes in Preparation (notice removed when complete)
Page Links: Introduction | Objectives | Lecture Audio | Textbooks | Abnormalities | References | Online Textbooks | Web Links | Web Movies | 2007 Lecture Slides | Comments | Acronyms

Objectives

• Understand the role of microfilaments in the cell

Lecture Audio

The University has a system for automated recording of lectures called Lectopia (or iLecture).

L12 Lectopia Recording | L13 Lectopia Recording

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Links: Lectopia Login Page | Cell Biology Podcast Page | Current Course Outline 2008

History

1887

Links:

Motility

• Motility is a fundamental cellular process
• embryonic development
• wound healing, blood vessel growth
• immune responses
• development of tissues
  • "human brain requires the laying down of about 1 million miles of neurites, all proceeding through the crawling motility of growth cones"

References

There is a complete list of online textbook links at 2008 ANAT3231 Lecture 11 - Microfilaments - References

Search Pubmed Articles "microfilament"

Essential Cell Biology - Chapter 16 p527-542

Molecular Biology of the Cell 4th ed. Chapter 16 p821 Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Raff, Martin; Roberts, Keith; Walter, Peter New York and London: Garland Science; c2002

The Cell - A Molecular Approach - Cooper, Geoffrey M. Sunderland (MA): Sinauer Associates, Inc. ; c2000

Molecular Cell Biology - Chapter 19 Lodish, Harvey; Berk, Arnold; Zipursky, S. Lawrence; Matsudaira, Paul; Baltimore, David; Darnell, James E. New York: W. H. Freeman & Co. ; c1999

Microfilaement references

Medline (April) Reference Search Results

• Actin 62,901 (08) 58,545 (07) 54,273 (06) 50,096 (05) 46,353 (04)
• Actin Binding Proteins 63,038 (08) 59,067 (07) 54,711 (06) 50,620 (05) 46,945 (04)
• Myosin 30,500 (08) 29,099 (07) 27,683 (06) 26,286 (05) 24,924 (04)

There is a complete list of online textbook links at 2008 ANAT3231 Lecture 11 - Microfilaments - References

Web Links

Web Movies

Molecular Cell Biology

First link is directly to Quicktime move, followed by associated textbook figure with legend. Look at the movie first, then look at the labelled image.

MCB - Photosynthesis | The primary event in photosynthesis

Theriot Lab

Theriot Lab Movie Collection

Shows a collection of educational videos featuring many pathgoens. Some of were featured in the Discovery channel documentry "Intimate Strangers."

Borisy Lab

Borisy Lab Movie Page

Shows a collection of all available supplemental movies for publications

Pollard Lab

Pollard Lab Movie Page

1. Fission yeast mitosis and cytokinesis. 2. Actin filament branching by Arp2/3 complex.

Robinson Lab

The Structural Biology of Cell Movement - Gelsolin Movies

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Acronyms

• ABP - Actin Binding Protein
• ADP - Adenosine Diphosphate
• ARP - Actin-related proteins
• ATP - Adenosine Triphosphate
• DNA - deoxyribonucleic acid
• EM - electron microscopy
• f actin - Filamentous actin polymer
• FL - flourescent
• g actin - Globular actin monomer
• MF - Microfilament
• OMIM - Online Mendelian Inheritance in Man Database
• PDF - Portable Document Format (electronic paper)
• Wasp - Wiskott-Aldrich Syndrome Protein

2007 Lecture Slides

(MH - note that content will not match exactly current lecture structure but has been selected as having similar content)

lecture07 1 slide/page (view only) (55 pages, 1.7 Mb)

lecture07 4 slides/page (print) (14 pages, 932 Kb)

lecture07 outline (print no images) (7 pages, 160 Kb)

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Links: Download Acrobat Reader 8.0

Working Window

Comments

 

	In 2008 a new way of presenting course content online is being trialled. Please let me know of any difficulties/suggestions or things that work well. Notice also that in some slides I have added annotations in brackets with my initials (MH - )
	Links: Current Course Outline 2008