UNSW Cell Biology

ANAT3231 Lecture 08 Extracellular Matrix

Introduction

Outside of the cell is the extracellular matrix (ECM). This matrix, even from a basic list of its components; proteins, glycoproteins, glycosaminoglycans, and many other large and small biological molecules, can been seen as complex. Furthermore there is no one specific ECM with great variation from tissue to tissue and also specific functional specializations. The lecture will attempt therefore to only cover a few key concepts on this topic.

The key concepts are: extracellular matrix, collagen, proteoglycans, fibronectin, laminin, basal lamina, basement membrane, adhesion, signaling, focal contacts, integrins

The lecture slides and textbook alone contain enough information as an introduction to the subject for this level of study. If you are interested in further reading, I have also included below links to more detailed textbooks with further information and images. Please note this additional information is not necessarily examinable, but may be useful if you have not previously studied biology. The link below to lecture slides allows you to open and view the slides in your web browser or download the PDF document for later viewing/printing.

Objectives

Understand the role of the extracellular matrix

Understand the components of the extracellular matrix

Understand the structure and synthesis of collagen fibers

Brief understanding of proteoglycan structure and function

Brief understanding of fibronectin and lamin structure and function

Lecture Slides

Link to lecture slides allows you to open and view the slides in your web browser or download the PDF document for later viewing/printing.

lecture08 1 slide/page (view only) (43 pages, 1.8 Mb)

lecture08 4 slides/page (print) (11 pages, 620 Kb)

lecture08 outline (print no images) (6 pages, 156 Kb)

NLM Online Textbooks

Molecular Biology of the Cell
XX

Molecular Cell Biology
Summary

The Cell- A Molecular Approach

Search NLM Online Textbooks- "apoptosis"

Molecular Biology of the Cell

Molecular Cell Biology

The Cell- A molecular Approach

Textbooks

Library: Local List | NCBI Bookshelf

Web Links

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