This lecture is an introduction to cellular organelles, beginning with those organelles involved in protein synthesis and export. The key components are: nucleus, rough endoplasmic reticulum, smooth endoplasmic reticulum, golgi apparatus, transport vesicles, secretory vesicles, endosomes. The lecture slides and textbook alone contain enough information as an introduction to the subject for this level of study. If you are interested in further reading, I have also included below links to more detailed textbooks with further information and images. Please note this additional information is not necessarily examinable, but may be useful if you have not previously studied biology.
Understand role of each cellular organelle involved in protein synthesis and export/import
Understand the function and transport of vesicles in the cytoplasm
Brief understanding of types of protein modification
Brief understanding of secretion (exocytosis) and absorbtion (endocytosis)
Understanding of what cells secrete and absorb
Page Links: Lectopia Audio | Lecture Slides | NLM Online Textbooks | Search PubMed | Web Links | OMIM Database | Related Topics
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Cell Organelles 1 - Lecture Slides 1/page (viewing only) (51 pages, 964 Kb)
Cell Organelles 1 - Lecture Slides 4/page (printing) (13 pages, 476 Kb)
Cell Organelles 1 - Lecture Slide Outline (printing no images) (5 pages, 100 Kb)
The Endoplasmic Reticulum
Image: The Endoplasmic Reticulum
Search MBoC4 "Endoplasmic Reticulum" (53 items)
The Golgi Apparatus Consists of an Ordered Series of Compartments
Image: The functional compartmentalization of the Golgi apparatus
Image: Two possible models explaining the organization of the Golgi apparatus
Search MBoC4 "Golgi apparatus" (90 items)
Intracellular Vesicular Traffic
The formation of secretory vesicles
Rough Endoplasmic Reticulum
Smooth Endoplasmic Reticulum
Search MCB "Endoplasmic Reticulum" (49 items)
Golgi Vesicles Process and Sort Secretory and Membrane Proteins
Search MCB "Golgi apparatus" (12 items)
Image: The secretory pathway of protein synthesis and sorting
Movie: Organelle Protein Sorting (Note large size - 12.4 Mb)
Movie: Protein Synthesis Endoplasmic Reticulum (Note large size - 5.8 Mb)
The Endoplasmic Reticulum
Image: Topology of the secretory pathway
Search The Cell "Endoplasmic Reticulum" (42 items)
The Golgi Apparatus
Search The Cell "Golgi apparatus" (38 items)
The Links below will carry out automated searches of the PubMed database using the showmn criteria.
Endoplasmic Reticulum (title, reviews, Published from 2004)
Golgi Apparatus (title, reviews, Published from 2004)
Secretory Vesicle (title, reviews, Published from 2004)
Protein Synthesis (title, reviews, Published from 2004)
External link to NLM PubMed Database, listed references are cross section of all (201) recent reviews, use the Search option to see all Reviews
Mattaj IW. Sorting out the nuclear envelope from the endoplasmic reticulum. Nat Rev Mol Cell Biol. 2004 Jan;5(1):65-9. Review.
Voeltz GK, Rolls MM, Rapoport TA. Structural organization of the endoplasmic reticulum. EMBO Rep. 2002 Oct;3(10):944-50. Review.
Papp S, Dziak E, Michalak M, Opas M. Is all of the endoplasmic reticulum created equal? The effects of the heterogeneous distribution of endoplasmic reticulum Ca2+-handling proteins. J Cell Biol. 2003 Feb 17;160(4):475-9. Review.
Staehelin LA. The plant ER: a dynamic organelle composed of a large number of discrete functional domains. Plant J. 1997 Jun;11(6):1151-65. Review.
Rios RM, Bornens M. The Golgi apparatus at the cell centre. Curr Opin Cell Biol. 2003 Feb;15(1):60-6. Review.
Short B, Barr FA. The Golgi apparatus. Curr Biol. 2000 Aug 24;10(16):R583-5. Review.
Barr FA. Inheritance of the endoplasmic reticulum and Golgi apparatus. Curr Opin Cell Biol. 2002 Aug;14(4):496-9. Review.
Storrie B, Nilsson T. The Golgi apparatus: balancing new with old. Traffic. 2002 Aug;3(8):521-9. Review.
Articles "cell organelles" | last 90 days | last 1 year | last 2 years | last 5 years | all articles |
Golgi Complex: Structure and Function
about Camille Golgi (1843 -1926)
Nobel Prize Site Biography Camille Golgi
About this Database from NCBI: "This database is a catalog of human genes and genetic disorders authored and edited by Dr. Victor A. McKusick and his colleagues at Johns Hopkins and elsewhere, and developed for the World Wide Web by NCBI, the National Center for Biotechnology Information. The database contains textual information and references. It also contains copious links to MEDLINE and sequence records in the Entrez system, and links to additional related resources at NCBI and elsewhere."
Search List 2005
Exocytosis (70 items)
Endocytosis (134 items)
Endoplasmic Reticulum (473 items)
Golgi apparatus (119 items)
Transport Vesicles (128 items)
gene expression, RNA, messenger RNA, transport RNA, ribosomal RNA, nucleolus, nuclear pores, endoplasmic reticulum, rough endoplasmic reticulum, smooth endoplasmic reticulum, protein sorting, glycosylation, transport vesicles, microtubules, Golgi apparatus, secretory vesicles
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