A major difference between eukayotes and prokaryotes is the presence of physical compartments (membrane bound) within the cell. These compartments allow the separation/specialization of processes within the cell.
There also exist within each of these physical compartments, functional compartments where specific processes may occur or are restricted too.
This lecture is an introduction to compartments within the cell and membranes. The key components are: cell compartments, membrane structure, membrane models, membrane specializations. The lecture slides and textbook alone contain enough information as an introduction to the subject for this level of study. If you are interested in further reading, I have also included below links to more detailed textbooks with further information and images. Please note this additional information is not necessarily examinable, but may be useful if you have not previously studied biology. The link below to lecture slides allows you to open and view the slides in your web browser or download the PDF document for later viewing/printing.
Understand the structural difference between eukaryotes and prokaryotes
Understand the concept of separate intracellular spaces
Understand the structure of membranes
Brief understanding of history of membrane models
Understand the difference between physical and functional compartments
Understanding of the types of transport across membranes
Link to lecture slides allows you to open and view the slides in your web browser or download the PDF document for later viewing/printing. Download Acrobat Reader 6.0
Lecture Slides 1/page (viewing only) (42 pages, 1.1 Mb)
Lecture Slides 4/page (printing) (11 pages, 736 kb)
Lecture Slide Outline (printing no images) (5 pages, 116 Kb)
Note that until week of current lecture each link above will be to the previous year.
Due to the automated recording method, most lectures begin 4-5 minutes into MP3 recordings.
MBoC | Publisher (Garland) MBoC
The Compartmentalization of Cells
Image: Hypothetical schemes for the evolutionary origins of some membrane-enclosed organelles
Image: The major intracellular compartments of an animal cell.
Image: Topological relationships between compartments in a eucaryotic cell
Image: 3 views of plasma membrane
Table: Relative Amounts of Membrane Types in Two Types of Eucaryotic Cells
The Cells of the Vertebrate Body Exhibit More Than 200 Different Modes of Specialization
Search Links: Plasma Membrane (357 items)
patches and slippery rafts: scales of domains in the plasma membrane
Trends Cell Biol. 2001 Dec;11(12):492-6. Review
Lipid Rafts References
Functions of Lipid Rafts in biological Membranes Annu. Rev. Cell. Dev. Biol. 1998, Vol. 14: 111-136
Synaptic Vesicle Biogenesis Annu. Rev. Cell. Dev. Biol. 1999, Vol. 15: 733-798
PubmedJournal Database| Journal List link | Journal Links by Journal Title
lipid, cholesterol, membrane proteins