UNSW Cell Biology

Medicine: Society and Health: Nucleus

Introduction

Nucleus is holder of the cell's genetic imformation in the form of DNA. This double membraned organelle forms a compartment where gene expression occurs and has specialized channels "nuclear pores" which allow the import of protein and the export of messenger RNA. The nuclear membrane is also continuous with the endoplasmic reticulum.

When a cell divides, the nucleus reorganises; firstly duplicating DNA and refolding into chromosomes, then in mitosis the nuclear membrane breaks down, to reform in the daughter cells.

Student Guide

Brief Study (1-15 minutes)

Start by looking at the online textbooks. These links will give you an introduction to the nucleus and some images.

Detailed Study (15-30 minutes)

Next- more detailed online resources introduce key features and functions of the nucleus. Includes a link to a complete set of lecture slides on Nucleus.

In Depth (+30 minutes)

Then- look at key research articles on the nucleus.

Includes links to review articles and animations.

Links

Search NLM Online Textbooks- "Nucleus"

Molecular Biology of the Cell (4th edition)

Molecular Biology of the Cell (3rd edition)

Molecular Cell Biology

The Cell- A molecular Approach

Related Topics

BGD DNA, BGD chromosomes, BGD genome, BGD transcription, nucleolus, nuclear matrix, nuclear pores, intermediate filaments, lamins, steroid hormones,