Non-dysjunction and aneuploidy are related to segregation of chromosomes during the cell cycle. In development, when the
male and female pronuclei combine and first divide is a critical step.
Start by looking at the online textbooks.
These links will give you an introduction to cell division and chromosome segregation.
Next- more detailed online resources introduce.
Includes a link to a complete set of lecture slides on cell division.
Then- look at the current research on chromosome non-dysjunction and aneuploidy.
Includes links to review articles and animations.Search NLM Online Textbooks- "aneuploidy"
Search NLM Online Textbooks- "non-dysjunction"
cell division, mitosis, trisomy