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UNSW Cell Biology

Endoplasmic Reticulum

Introduction

The endoplasmic reticulum is a single membrane bound cytoplasmic compartment, with two specialized functional compartments: rough endoplasmic reticulum (RER) and smooth endoplasmic reticulum (SER).

NLM Online Textbooks

Molecular Biology of the Cell (4th ed.) Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Raff, Martin; Roberts, Keith; Walter, Peter New York: Garland Publishing. (c2002)

Image: The Endoplasmic Reticulum

Intracellular Compartments and Protein Sorting

Molecular Cell Biology (4th ed.) Lodish, Harvey; Berk, Arnold; Zipursky, S. Lawrence; Matsudaira, Paul; Baltimore, David; Darnell, James E. New York: W. H. Freeman & Co. (c2000)

The Cell- A Molecular Approach (2nd ed.) Cooper, Geoffrey M. Sunderland (MA): Sinauer Associates, Inc (c2000)

Movies

Molecular Cell Biology (4th ed.) Lodish, Harvey; Berk, Arnold; Zipursky, S. Lawrence; Matsudaira, Paul; Baltimore, David; Darnell, James E. New York: W. H. Freeman & Co. (c2000)

First link is directly to Quicktime move, followed by associated textbook figure with legend. Look at the movie first, then look at the labelled image.

MCB - Protein Sorting | Figure 17-1. Overview of sorting of nuclear-encoded proteins in eukaryotic cells

MCB - Life Cycle of an mRNA | Figure 4-42. Model of protein synthesis on circular polysomes and recycling of ribosomal subunits

MCB - Synthesis of Secreted and Membrane-Bound Proteins | Figure 17-16. Synthesis of secretory proteins on the rough ER

MCB - Protein Secretion | Figure 17-13. The secretory pathway of protein synthesis and sorting

Web Links

NIH Endoplasmic Reticulum

Smooth Endoplasmic Reticulum

Where to Next

Medicine - module developed to support new medical curriculum
Science - module developed to support ANAT3231 course
About- Describes how the project website was designed
Lab Methods - some current Lab methods
Methods - brief description of cell biology methods
History - timeline of key discoveries
Glossary - list of terms and acronyms
Links - list of key internet links
Library- list of resource, including online textbooks, used in generating information on this site.
Questions- start with a question about Cell Biology. Problems- start with a problem in Cell Biology.